BDBM247177 US9434733, 2-[4-methyl-1-[[4-(trifluoromethyl)phenyl]methyl]pyrrolidin-3-yl]-7-tetrahydropyran-4-yl-3H-imidazo[5,1-f][1,2,4]triazin-4-one::US9533992, 2-[4-methyl-1-[[4-(trifluoromethyl)phenyl]methyl]pyrrolidin-3-yl]-7-tetrahydropyran-4-yl-3H-imidazo[5,1-f][1,2,4]triazin-4-one
SMILES CC1CN(Cc2ccc(cc2)C(F)(F)F)CC1c1nn2c(ncc2c(=O)[nH]1)C1CCOCC1
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 247177
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 12nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 12nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 12nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair